xtramedullary plasmacytoma frequently remain localized and display lower incidence of conversion to multiple myeloma than do solitary plasmacytoma of bone. If histologic diagnosis of plasmacytoma is comfirmed, all screening tests to rule out
multiple
myeloma is neccesary before initial treatment and during follow-up period.
Histologic diagnosis of plasmacytoma of maxillary sinus was made in made in two cases. Radiotherapy was given post-operatively. In first case, serum and urine electrophoresis demonstrated monoclonal gammopathy. other tests including bone marrow
biopsy
and X-ray survey in order to rule out multiple myeloma were not performed in first patient. In second case, all screenig tests were negative. The two patients complained of bone pain. So, serum and urine electrophoresis, X-ray survey, bone marrow
aspiration biopsy were performed, the findings were consistent with multiple myeloma. Two cases were diagnosed as extramedullary plasmacytoma converted to multiple myeloma. Chemotherapy was begun, continued to 15th cycle in first patients, 19th
cycle in
second patients. (Korean J Otolaryngol 39 : 3, 1996)
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